Nicholas M. Frame

Structure of serum amyloid A suggests a mechanism for selective lipoprotein binding and functions: <scp>SAA</scp> as a hub in macromolecular interaction networks

Nicholas M. Frame, Olga Gursky · FEBS Letters · 2016 · 53 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease

Elena S. Klimtchuk, Tatiana Prokaeva, Nicholas M. Frame et al. · Proceedings of the National Academy of Sciences · 2018 · 32 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Serum amyloid A self-assembles with phospholipids to form stable protein-rich nanoparticles with a distinct structure: A hypothetical function of SAA as a “molecular mop” in immune response

Nicholas M. Frame, Shobini Jayaraman, Donald Gantz · Journal of Structural Biology · 2017 · 28 citations · Full text

Life Sciences, Biochemistry, Immunology +17

Structure of serum amyloid A suggests a mechanism for selective lipoprotein binding and functions: SAA as a hub in macromolecular interaction networks

Nicholas M. Frame, Olga Gursky · Amyloid · 2016 · 23 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Structural Basis for Lipid Binding and Function by an Evolutionarily Conserved Protein, Serum Amyloid A

Nicholas M. Frame, Meera Kumanan, Thomas E. Wales et al. · Journal of Molecular Biology · 2020 · 22 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17