ATP-Dependent Dynamic Protein Aggregation Regulates Bacterial Dormancy Depth Critical for Antibiotic Tolerance

Yingying Pu, Yingxing Li, Xin Jin, +10

Molecular Cell

Prokaryotic SystemAntibiotic ToleranceBacteriologyMolecular BiologyMicrobiology +4

Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways

Bing Huang, Zhanghua Chen, Lanlan Geng, +39

Cell

InflammationPediatric-onset ColitisMucosal ImmunologyPathogenesisImmunology +11

Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19

Xiaoyan Liu, Zhe Li, Shuai Liu, +22

Acta Pharmaceutica Sinica B

Macroscopic somatic clonal expansion in morphologically normal human urothelium

Ruoyan Li, Yiqing Du, Zhanghua Chen, +9

Science

ACE2 expression by colonic epithelial cells is associated with viral infection, immunity and energy metabolism

Jun Wang, Shanmeizi Zhao, Ming Liu, +15

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationInnate Immune SystemImmunology +25

Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia

Jun Wang, Yanhui Xu, Zhanghua Chen, +33

Cell

ImmunologyPathologyCirrhosisAutoimmune Liver DiseaseInflammation +15

Therapeutic effects of dipyridamole on COVID-19 patients with coagulation dysfunction

Xiaoyan Liu, Zhe Li, Shuai Liu, +21

ThrombosisDip SupplementationCoagulation DysfunctionMedicineDrug Library +12

Excessive deubiquitination of NLRP3-R779C variant contributes to very-early-onset inflammatory bowel disease development

Lingli Zhou, Tao Liu, Bing Huang, +24

Journal of Allergy and Clinical Immunology

InflammationAutoimmune DiseaseImmunologyGastroenterologyChronic Inflammation +6

MCM8-mediated mitophagy protects vascular health in response to nitric oxide signaling in a mouse model of Kawasaki disease

Meng Lin, Huifang Xian, Zhanghua Chen, +30

Nature Cardiovascular Research

InflammationCytokineMitophagyMcm8-mediated MitophagyAutoimmune Disease +13

Aneuploid embryonic stem cells drive teratoma metastasis

Rong Xiao, Deshu Xu, Meili Zhang, +8

Nature Communications