Janice H. Xu

Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells

Jeanne G. Quirit, Sergey N. Lavrenov, Kevin M. Poindexter et al. · Biochemical Pharmacology · 2016 · 72 citations

Disrupt Proliferation, Medicine, Melanoma +7

Discovery of small-molecule enzyme activators by activity-based protein profiling

Bernard P. Kok, Srijana Ghimire, Woojoo E. Kim et al. · Nature Chemical Biology · 2020 · 48 citations · Full text

Biochemistry, Natural Sciences, Enzyme Specificity +4

Quantitative Metaproteomics and Activity-based Protein Profiling of Patient Fecal Microbiome Identifies Host and Microbial Serine-type Endopeptidase Activity Associated With Ulcerative Colitis

Peter Thuy-Boun, Ana Y. Wang, Ana Crissien-Martinez et al. · Molecular & Cellular Proteomics · 2022 · 41 citations · Full text

Inflammation, Dysbiosis, Medicine +15

A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides <i>in Vitro</i>

Janice H. Xu, Zhenze Jiang, Angelo Solania et al. · ACS Chemical Biology · 2018 · 18 citations · Full text

Integrative X-ray Structure and Molecular Modeling for the Rationalization of Procaspase-8 Inhibitor Potency and Selectivity

Janice H. Xu, Jérôme Eberhardt, Brianna Hill-Payne et al. · ACS Chemical Biology · 2020 · 16 citations · Full text