Intestinal fungi contribute to development of alcoholic liver disease

An-Ming Yang, Tatsuo Inamine, K Hochrath, +26

Journal of Clinical Investigation

Chronic Inflammatory DiseasesChronic Alcohol AdministrationMicrobial PathogensImmunologyImmune Regulation +18

Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation

Lirui Wang, Derrick E. Fouts, Peter Stärkel, +9

Cell Host & Microbe

InflammationDysbiosisMucosal ImmunologyPathogenesisImmunology +10

Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice

Phillipp Hartmann, K Hochrath, Angela Horvath, +18

Hepatology

Gut microbiota from NLRP3-deficient mice ameliorates depressive-like behaviors by regulating astrocyte dysfunction via circHIPK2

Yuan Zhang, Rongrong Huang, Mengjing Cheng, +7

Microbiome

Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus

Cristina Llorente, Peter Jepsen, Tatsuo Inamine, +18

Nature Communications

Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice

Phillipp Hartmann, Peng Chen, Hui Wang, +9

Hepatology

Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice

Magdalena Mazagova, Lirui Wang, Andrew Anfora, +10

The FASEB Journal

DysbiosisImmunologyPathologyConventional MiceCirrhosis +23

Passion fruit-like exosome-PMA/Au-BSA@Ce6 nanovehicles for real-time fluorescence imaging and enhanced targeted photodynamic therapy with deep penetration and superior retention behavior in tumor

Shaojun Pan, Lijia Pei, Amin Zhang, +9

Biomaterials

NanomedicineEngineeringPhotodynamic TherapyBiomedical ImagingTherapeutic Imaging +6

Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling

Shaojun Pan, Yuhui Zhang, Mark Huang, +8

Biomaterials

NanomedicineUrologyEgfr/akt/nf-kb/ikb SignalingEngineeringGenitourinary Cancer +6

Vitamin A-decorated biocompatible micelles for chemogene therapy of liver fibrosis

Jian-Bin Qiao, Qianqian Fan, Lei Xing, +8

Journal of Controlled Release

NanomedicineFibrosisChemogene TherapyHepatologyPolymer-drug Conjugate +9