FOXO3a regulates BNIP3 and modulates mitochondrial calcium, dynamics, and function in cardiac stress

Antoine H. Chaanine, Erik Kohlbrenner, Scott I. Gamb, +6

American Journal of Physiology-Heart and Circulatory Physiology

Experimental cardiac radiation exposure induces ventricular diastolic dysfunction with preserved ejection fraction

Hirofumi Saiki, Gilles Moulay, Adam J. Guenzel, +8

American Journal of Physiology-Heart and Circulatory Physiology

Generation of a Hypomorphic Model of Propionic Acidemia Amenable to Gene Therapy Testing

Adam J. Guenzel, Sean Hofherr, Matthew L. Hillestad, +1

Molecular Therapy

The critical role of psychosine in screening, diagnosis, and monitoring of Krabbe disease

Adam J. Guenzel, Coleman Turgeon, Kim K. Nickander, +21

Genetics in Medicine

Clinical DisordersPsychiatryCritical RoleDiagnosisMedicine +2

In vivo evidence of mitochondrial dysfunction and altered redox homeostasis in a genetic mouse model of propionic acidemia: Implications for the pathophysiology of this disorder

Lorena Gallego‐Villar, Ana Rivera‐Barahona, Carmen Cuevas-Martín, +11

Free Radical Biology and Medicine

Mitochondrial FunctionBiochemistryMitochondrial DysfunctionGeneticsPhysiology +8

Long-Term Sex-Biased Correction of Circulating Propionic Acidemia Disease Markers by Adeno-Associated Virus Vectors

Adam J. Guenzel, Renata Collard, Jan P. Kraus, +2

Human Gene Therapy

Mitochondrial Integrity and Function in the Progression of Early Pressure Overload–Induced Left Ventricular Remodeling

Antoine H. Chaanine, K. Sreekumaran Nair, Robert H. Bergen, +4

Journal of the American Heart Association

Cardiac AAV9 Gene Delivery Strategies in Adult Canines: Assessment by Long-term Serial SPECT Imaging of Sodium Iodide Symporter Expression

Gilles Moulay, Tomohito Ohtani, Ozgur Ogut, +12

Molecular Therapy

A Vector–Host System to Fingerprint Virus Tropism

Matthew L. Hillestad, Adam J. Guenzel, Karl A. Nath, +1

Human Gene Therapy

Systems BiologyFingerprint Virus TropismReporter Gene AssayVirus PhylogenyReporter Gene Feedback +10

Pathogenic implications of dysregulated miRNAs in propionic acidemia related cardiomyopathy

Alejandro Fulgencio-Covián, Esmeralda Alonso-Barroso, Adam J. Guenzel, +7

Translational research

CardiomyopathyHeart FailurePropionic AcidemiaCardiovascular DiseasePhysiology +9