Alisha Holtzhausen

Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization

Fei Zhao, Christine Xiao, Kathy S. Evans et al. · Immunity · 2018 · 287 citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +12

A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti–PD-1 immunotherapy

Balamayoora Theivanthiran, Kathy S. Evans, Nicholas C. DeVito et al. · Journal of Clinical Investigation · 2020 · 235 citations · Full text

Immunology, Immunotherapy Resistance, Immunotherapeutics +19

Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response

Eric Ubil, Laura S. Caskey, Alisha Holtzhausen et al. · Journal of Clinical Investigation · 2018 · 209 citations · Full text

Immunology, Immune Regulation, Immunologic Mechanism +18

Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of Immunotherapy

Alisha Holtzhausen, Fei Zhao, Kathy S. Evans et al. · Cancer Immunology Research · 2015 · 175 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +25

TAM Family Receptor Kinase Inhibition Reverses MDSC-Mediated Suppression and Augments Anti–PD-1 Therapy in Melanoma

Alisha Holtzhausen, William P. Harris, Eric Ubil et al. · Cancer Immunology Research · 2019 · 121 citations