Edwin Roovers

Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors.

Martine J. Smit, Rob Leurs, A. E. Alewijnse et al. · Proceedings of the National Academy of Sciences · 1996 · 245 citations

Medicine, Pharmacology, Cell Signaling +13

The Effect of Mutations in the DRY Motif on the Constitutive Activity and Structural Instability of the Histamine H2 Receptor

Astrid E. Alewijnse, Henk Timmerman, Edwin H. Jacobs et al. · Molecular Pharmacology · 2000 · 194 citations

Life Sciences, Biochemistry, Pharmacology +17

Chemoattractant and guanosine 5′-[<i>γ</i>-thio]triphosphate induce the accumulation of inositol 1,4,5-trisphosphate in <i>Dictyostelium</i> cells that are labelled with [3H]inositol by electroporation

Peter J.M. Van Haastert, Martinus J. De Vries, Louis C. Penning et al. · Biochemical Journal · 1989 · 109 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13

The telomeric part of the HLA region predisposes to rheumatoid arthritis independently of the class II loci

Eric Zanelli, Gavin C. Jones, M. Pascual et al. · Human Immunology · 2001 · 67 citations

Life Sciences, Genetics, Immunology +14

Characterization of a putative molluscan insulin-related peptide receptor

Edwin Roovers, Muriel E. Vincent, Ellen van Kesteren et al. · Gene · 1995 · 65 citations

Life Sciences, Biochemistry, Molecular Biology +9