Margaret A. Pigott

Optically active benzo[c]phenanthrene diol epoxides bind extensively to adenine in DNA

Anthony Dipple, Margaret A. Pigott, Shiv Kumar Agarwal et al. · Nature · 1987 · 114 citations

Nucleic Acid Chemistry, Bioorganic Chemistry, Biochemistry +9

Evidence that binding of 7,12-dimethylbenz(a)anthracene to DNA in mouse embryo cell cultures results in extensive substitution of both adenine and guanine residues.

Anthony Dipple, Margaret A. Pigott, Robert C. Moschel et al. · PubMed · 1983 · 112 citations

Chromatin, Deoxyadenosine Adduct, Nucleic Acid Chemistry +15

Chemical characterization of DNA adducts derived from the configurationally isomeric benzo[c]phenanthrene-3,4-diol 1,2-epoxides

Shiv Kumar Agarwal, Jane M. Sayer, Herman J. C. Yeh et al. · Journal of the American Chemical Society · 1987 · 88 citations

Molecular Characterization, Molecular Sciences, Dna +14

Reactivity and Tumorigenicity of Bay-Region Diol Epoxides Derived from Polycyclic Aromatic Hydrocarbons

D. M. JERINA, Jane M. Sayer, Shiv Kumar Agarwal et al. · Advances in experimental medicine and biology · 1986 · 59 citations

Derivatives, Organic Chemistry, Polycyclic Aromatic Hydrocarbons +4

A metabolite of the carcinogen 7,12-dimethylbenz[<i>a</i>]anthracene that reacts predominantly with adenine residues in DNA

Siyao Cheng, A. S. Prakash, Margaret A. Pigott et al. · Carcinogenesis · 1988 · 57 citations