The basolateral amygdala-anterior cingulate pathway contributes to depression-like behaviors and comorbidity with chronic pain behaviors in male mice

Léa J. Becker, Clémentine Fillinger, Robin Waegaert, +19

Nature Communications

Chronic Pain BehaviorsChronic Pain-induced DepressionAffective NeuroscienceMolecular PainSocial Sciences +19

Design, synthesis and evaluation of novel multi-target-directed ligands for treatment of Alzheimer's disease based on coumarin and lipoic acid scaffolds

Leili Jalili‐Baleh, Hamid Forootanfar, Tuba Tüylü Küçükkılınç, +13

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryAlzheimer's DiseaseBiochemistryNovel Multi-target-directed Ligands +8

Ketamine induces rapid and sustained antidepressant-like effects in chronic pain induced depression: Role of MAPK signaling pathway

Muris Humo, Beyza Ayazgök, Léa J. Becker, +3

Progress in Neuro-Psychopharmacology and Biological Psychiatry

PsychiatryPain MedicineAntidepressant-like EffectsMedicinePsychotropic Medication +12

Novel 3-phenylcoumarin–lipoic acid conjugates as multi-functional agents for potential treatment of Alzheimer's disease

Leili Jalili‐Baleh, Hamid Nadri, Hamid Forootanfar, +13

Bioorganic Chemistry

Multi-functional AgentsNeurodegenerative DiseasesAlzheimer's DiseaseBiochemistryMedicine +5

Novel multi-targeted agents for Alzheimer's disease: Synthesis, biological evaluation, and molecular modeling of novel 2-[4-(4-substitutedpiperazin-1-yl)phenyl]benzimidazoles

Keriman Ozadali‐Sari, Tuba Tüylü Küçükkılınç, Beyza Ayazgök, +2

Bioorganic Chemistry

Medicinal ChemistryBiochemistryMedicineNatural SciencesRational Drug Design +7

Synthesis and biological evaluation of new N-benzylpyridinium-based benzoheterocycles as potential anti-Alzheimer’s agents

Naeimeh Salehi, Bi Bi Fatemeh Mirjalili, Hamid Nadri, +10

Bioorganic Chemistry

Bioorganic ChemistryNew N-benzylpyridinium-based BenzoheterocyclesHeterocyclicNatural SciencesMedicine +7

New classes of carbazoles as potential multi-functional anti-Alzheimer’s agents

Niloufar Choubdar, Mostafa Golshani, Leili Jalili‐Baleh, +10

Bioorganic Chemistry

Molecular PharmacologyAlzheimer's DiseaseMedicinePharmacological AgentNew Classes +2

Chromone–lipoic acid conjugate: Neuroprotective agent having acceptable butyrylcholinesterase inhibition, antioxidant and copper-chelation activities

Leili Jalili‐Baleh, Hamid Nadri, Hamid Forootanfar, +8

DARU Journal of Pharmaceutical Sciences

BiochemistryMedicineChromone–lipoic Acid ConjugateNeuroprotectionCopper-chelation Activities +4

Design, synthesis, and biological evaluation of novel indanone-based hybrids as multifunctional cholinesterase inhibitors for Alzheimer's disease

Mohammad Shahrivar‐Gargari, Maryam Hamzeh‐Mivehroud, Salar Hemmati, +5

Journal of Molecular Structure

BiochemistryMedicineNovel Indanone-based HybridsBiological EvaluationDrug Development +4

Synthesis and neuroprotective activity of novel 1,2,4-triazine derivatives with ethyl acetate moiety against H 2 O2 and Aβ-induced neurotoxicity

Tuba Tüylü Küçükkılınç, Kamaledin Safari Yanghagh, Beyza Ayazgök, +6

Medicinal Chemistry Research

Medicinal ChemistryDerivative (Chemistry)BiochemistryEthyl Acetate MoietyNovel 1,2,4-Triazine Derivatives +9