Development of a non-viral multifunctional envelope-type nano device by a novel lipid film hydration method

Kentaro Kogure, Rumiko Moriguchi, Kentaro Sasaki, +3

Journal of Controlled Release

Lipid PreparationNanomedicineEngineeringNanomaterialsNanobiotechnology +2

Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation☆

Hidetaka Akita, Kentaro Kogure, Rumiko Moriguchi, +7

Journal of Controlled Release

NanoparticlesNanomedicineEngineeringImmunologyTherapeutic Vaccine +10

Multi-layered nanoparticles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process

Hidetaka Akita, Asako Kudo, Arisa Minoura, +8

Biomaterials

Membrane FusionNanoparticlesMembrane FormationEngineeringProtein Nanoparticles +5

An artificial virus-like nano carrier system: enhanced endosomal escape of nanoparticles via synergistic action of pH-sensitive fusogenic peptide derivatives

Kentaro Sasaki, Kentaro Kogure, Shinji Chaki, +7

Analytical and Bioanalytical Chemistry

NanoparticlesNanomedicineEngineeringPeptide EngineeringEndosomal Escape +6

Efficient MHC Class I Presentation by Controlled Intracellular Trafficking of Antigens in Octaarginine-modified Liposomes

Takashi Nakamura, Rumiko Moriguchi, Kentaro Kogure, +2

Molecular Therapy

A multifunctional envelope-type nano device for novel gene delivery of siRNA plasmids

Rumiko Moriguchi, Kentaro Kogure, Hidetaka Akita, +4

International Journal of Pharmaceutics

EngineeringNanobiotechnologySirna PlasmidsNano-drug DeliveryGene Delivery +4

Non-linear pharmacodynamics in a non-viral gene delivery system: Positive non-linear relationship between dose and transfection efficiency

Rumiko Moriguchi, Kentaro Kogure, Akitada Iwasa, +2

Journal of Controlled Release

Non-linear PharmacodynamicsPositive Non-linear RelationshipMedicineViral DynamicDrug Delivery Systems +6

Incorporation of polyinosine–polycytidylic acid enhances cytotoxic T cell activity and antitumor effects by octaarginine-modified liposomes encapsulating antigen, but not by octaarginine-modified antigen complex

Takashi Nakamura, Rumiko Moriguchi, Kentaro Kogure, +1

International Journal of Pharmaceutics

Octaarginine-modified Antigen ComplexCancer ImmunosurveillanceOctaarginine-modified LiposomesMedicineImmunology +8

Delivery of Condensed DNA by Liposomal Non-viral Gene Delivery System into Nucleus of Dendritic Cells

Takashi Nakamura, Rumiko Moriguchi, Kentaro Kogure, +8

Biological and Pharmaceutical Bulletin

EngineeringImmunologyGene DeliveryBiomedical EngineeringImmunotherapy +14

Octaarginine-Modified Liposomes Enhance Cross-Presentation by Promoting the C-Terminal Trimming of Antigen Peptide

Takashi Nakamura, Kouhei Ono, Yoshiteru Suzuki, +3

Molecular Pharmaceutics

Lipid PreparationAntigen PeptideMature Mhc-i PeptideBiochemistryNatural Sciences +12