A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

Colin S. Duckett, Victor E. Nava, Richard Gedrich, +6

The EMBO Journal

Baculovirus Iap GeneConserved FamilyMolecular VirologyPathogenesisViral Pathogenesis +8

Induction of Nuclear Factor κB by the CD30 Receptor Is Mediated by TRAF1 and TRAF2

Colin S. Duckett, Richard Gedrich, Molly C. Gilfillan, +1

Molecular and Cellular Biology

Signal TransductionNuclear Factor κBSignaling PathwayLymphoma CellsT-regulatory Cell +12

Phase 1/2 study of ARV-110, an androgen receptor (AR) PROTAC degrader, in metastatic castration-resistant prostate cancer (mCRPC).

Xīn Gào, Howard A. Burris, Jacqueline Vuky, +17

Journal of Clinical Oncology

Androgen ReceptorImmunologyProtac DegraderPharmacotherapyImmunotherapeutics +22

CD30 Contains Two Binding Sites with Different Specificities for Members of the Tumor Necrosis Factor Receptor-associated Factor Family of Signal Transducing Proteins

Richard Gedrich, Molly C. Gilfillan, Colin S. Duckett, +2

Journal of Biological Chemistry

ImmunologyImmune RegulationPathologyCell DeathImmunologic Mechanism +19

Antitumor activity of sorafenib in FLT3-driven leukemic cells

Daniel Auclair, David F. Miller, Victoria Yatsula, +15

Leukemia

Tumor BiologyAntitumor ActivityMedicineAnti-cancer AgentCancer Biology +2

Transcriptional repression of the c-fos gene by YY1 is mediated by a direct interaction with ATF/CREB

Qianqian Zhou, Richard Gedrich, D A Engel

Journal of Virology

Molecular RegulationGeneticsMolecular BiologyTranscription Factor Yy1Molecular Genetics +16

Oral Estrogen Receptor PROTAC Vepdegestrant (ARV-471) Is Highly Efficacious as Monotherapy and in Combination with CDK4/6 or PI3K/mTOR Pathway Inhibitors in Preclinical ER+ Breast Cancer Models

Sheryl M. Gough, John J. Flanagan, Jessica L.F. Teh, +27

Clinical Cancer Research

Current whole-body MRI applications in the neurofibromatoses

Shivani Ahlawat, Laura M. Fayad, Muhammad Shayan Khan, +149

Neurology

Sorafenib Inhibits Imatinib-Resistant KIT and Platelet-Derived Growth Factor Receptor β Gatekeeper Mutants

Teresa Guida, Suresh Anaganti, Livia Provitera, +5

Clinical Cancer Research

Anti‐KIT monoclonal antibody CDX‐0159 induces profound and durable mast cell suppression in a healthy volunteer study

Diego Alvarado, Marcus Maurer, Richard Gedrich, +14

Allergy