Michael Roguska

Humanization of murine monoclonal antibodies through variable domain resurfacing.

Michael Roguska, Jim Thuesen Pedersen, C Keddy et al. · Proceedings of the National Academy of Sciences · 1994 · 202 citations

Pharmacy, Biochemistry, Immunology +17

A comparison of two murine monoclonal antibodies humanized by CDR-grafting and variable domain resurfacing

Michael Roguska, Jan T. Pedersen, Andrew Henry et al. · Protein Engineering Design and Selection · 1996 · 67 citations · Full text

Pharmacy, Immunology, Molecular Biology +17

Comparison of Surface Accessible Residues in Human and Murine Immunoglobulin Fv Domains

Jan T. Pedersen, Andrew Henry, Stephen Searle et al. · Journal of Molecular Biology · 1994 · 55 citations

Life Sciences, Immunology, Molecular Biology +12

Long-acting protein drugs for the treatment of ocular diseases

Joy G. Ghosh, Andrew Nguyen, Chad E. Bigelow et al. · Nature Communications · 2017 · 54 citations · Full text

Pharmacy, Ophthalmology, Pharmacology +17

An increase in prolyl-4-hydroxylase activity occurs during the retinoic acid-induced differentiation of mouse teratocarcinoma stem cell lines F9 and P19.

Michael Roguska, Lorraine J. Gudas · Journal of Biological Chemistry · 1985 · 26 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +12