Yuki Hirokami

Design and Synthesis of Labystegines, Hybrid Iminosugars from LAB and Calystegine, as Inhibitors of Intestinal α-Glucosidases: Binding Conformation and Interaction for ntSI

Atsushi Kato, Zhao-Lan Zhang, Hongyao Wang et al. · The Journal of Organic Chemistry · 2015 · 38 citations

Pharmacy, Biochemistry, Medicinal Chemistry +13

N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors

Jérôme Désiré, Martine Mondon, Nathalie Fontelle et al. · Organic & Biomolecular Chemistry · 2014 · 28 citations

Pharmacy, Biochemistry, Medicinal Chemistry +14

Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors

Atsushi Kato, Yuki Hirokami, Kyoko Kinami et al. · Phytochemistry · 2015 · 22 citations

Pharmacy, Biochemistry, Medicinal Chemistry +12

Gem-difluoromethylated and trifluoromethylated derivatives of DMDP-related iminosugars: synthesis and glycosidase inhibition

Yi‐Xian Li, Kyoko Kinami, Yuki Hirokami et al. · Organic & Biomolecular Chemistry · 2016 · 20 citations

Life Sciences, Biochemistry, Medicinal Chemistry +12

Strategy for designing selective α-l-rhamnosidase inhibitors: Synthesis and biological evaluation of l-DMDP cyclic isothioureas

Shota Miyawaki, Yuki Hirokami, Kyoko Kinami et al. · Bioorganic & Medicinal Chemistry · 2016 · 13 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +16