Bofu Huang

De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma

Diana D. Shi, Milan R. Savani, Michael M. Levitt et al. · Cancer Cell · 2022 · 114 citations · Full text

Glioma, Tumor Heterogeneity, Oncogenic Agent +10

<i>(R)</i> -2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in <i>IDH</i> -Mutant Cancers

Kathryn Gunn, Matti Myllykoski, John Z. Cao et al. · Cancer Discovery · 2023 · 37 citations · Full text

Sensitivity of<i>VHL</i>mutant kidney cancers to HIF2 inhibitors does not require an intact p53 pathway

Laura Stransky, Sean M. Vigeant, Bofu Huang et al. · Proceedings of the National Academy of Sciences · 2022 · 32 citations · Full text

P53 Status, Pathology, Intact P53 Pathway +19

Suppression of DNA-damage checkpoint signaling by Rsk-mediated phosphorylation of Mre11

Chen Chen, Liguo Zhang, Nai-Jia Huang et al. · Proceedings of the National Academy of Sciences · 2013 · 31 citations · Full text

Dsb Sites, Cell Death, Molecular Biology +16

Metabolic Control of Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII)-mediated Caspase-2 Suppression by the B55β/Protein Phosphatase 2A (PP2A)

Bofu Huang, Chih‐Sheng Yang, Jeffrey Wojton et al. · Journal of Biological Chemistry · 2014 · 15 citations · Full text