Joy L. Silen

The αlytic protease pro-region does not require a physical linkage to activate the protease domain in vivo

Joy L. Silen, David A. Agard · Nature · 1989 · 231 citations

Protein Function, Protein Assembly, Protein Folding +10

Structural plasticity broadens the specificity of an engineered protease

Roger Bone, Joy L. Silen, David A. Agard · Nature · 1989 · 165 citations

Protein Assembly, Protein Folding, Natural Sciences +5

Analysis of prepro-alpha-lytic protease expression in Escherichia coli reveals that the pro region is required for activity

Joy L. Silen, Daniel N. Frank, A Fujishige et al. · Journal of Bacteriology · 1989 · 157 citations · Full text

E. Coli, Escherichia Coli Reveals, Proteasome +17

Protease pro region required for folding is a potent inhibitor of the mature enzyme

David Baker, Joy L. Silen, David A. Agard · Proteins Structure Function and Bioinformatics · 1992 · 117 citations

Screening for Novel Antimicrobials from Encoded Combinatorial Libraries by Using a Two-Dimensional Agar Format

Joy L. Silen, Amy T. Lu, Dennis Solas et al. · Antimicrobial Agents and Chemotherapy · 1998 · 62 citations · Full text

Engineering, Antibacterial Activity, Encoded Combinatorial Libraries +20