Matthew J. Scheffel

Efficacy of Adoptive T-cell Therapy Is Improved by Treatment with the Antioxidant N-Acetyl Cysteine, Which Limits Activation-Induced T-cell Death

Matthew J. Scheffel, Gina Scurti, Patricia Simms et al. · Cancer Research · 2016 · 72 citations · Full text

Cell Therapy, T-regulatory Cell, Immunology +27

N-acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner

Matthew J. Scheffel, Gina Scurti, Megan M. Wyatt et al. · Cancer Immunology Immunotherapy · 2018 · 46 citations · Full text

Cancer Immunosurveillance, Rapid Expansion, Medicine +9

T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules

Navtej Kaur, Osama Naga, Håkan Norell et al. · Cytokine · 2011 · 38 citations · Full text

Inflammation, Cytokine, Autoimmune Disease +12

Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner

Tejas Tirodkar, Ping Lü, Aiping Bai et al. · Journal of Biological Chemistry · 2015 · 37 citations · Full text

Lack of <i>p53</i> Augments Antitumor Functions in Cytolytic T Cells

Anirban Banerjee, Krishnamurthy Thyagarajan, Shilpak Chatterjee et al. · Cancer Research · 2016 · 37 citations · Full text