Donald J. Creighton

Reaction Mechanism of Glyoxalase I Explored by an X-ray Crystallographic Analysis of the Human Enzyme in Complex with a Transition State Analogue

Alexander D. Cameron, Marianne Ridderström, B. Olin et al. · Biochemistry · 1999 · 129 citations

<i>N</i>-(2-Hydroxypropyl)methacrylamide Copolymers of a Glutathione (GSH)-Activated Glyoxalase I Inhibitor and DNA Alkylating Agent:  Synthesis, Reaction Kinetics with GSH, and in Vitro Antitumor Activities

Zhe-Bin Zheng, Guo‐Zhang Zhu, Heekyung Tak et al. · Bioconjugate Chemistry · 2005 · 88 citations

Model dehydrogenase reactions. Zinc ion catalyzed reduction of chelating aldehydes by N-propyl-1,4-dihydronicotinamides and borohydride

Donald J. Creighton, Joseph Hajdu, David S. Sigman · Journal of the American Chemical Society · 1976 · 84 citations

Engineering, Aldehyde Dehydrogenase, Biochemistry +11

Optimization of efficiency in the glyoxalase pathway

Donald J. Creighton, Molly Migliorini, Tayebeh Pourmotabbed et al. · Biochemistry · 1988 · 84 citations

Active Monomeric and Dimeric Forms of <i>Pseudomonas putida</i> Glyoxalase I:  Evidence for 3D Domain Swapping

Andre Saint-Jean, Kristina R. Phillips, Donald J. Creighton et al. · Biochemistry · 1998 · 75 citations