Concepedia

Author

Mary Ann Powles

Merck & Co., Inc., Rahway, NJ, USA (United States)

Also Known As

Mary Ann Powles

18

Publications

659

Citations

13

H-Index

40

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)
MA

About

Mary Ann Powles is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

9

9

433

2

Biochemistry

6

6

351

3

Natural Sciences

3

3

102

4

Engineering

1

1

92

5

Health Sciences

1

1

77

Mary Ann Powles

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14

Publications

652

Citations

13

H-Index

YearCitations

Efficacy of MK-991 (L-743,872), a Semisynthetic Pneumocandin, in Murine Models of <i>Pneumocystis carinii</i>

Mary Ann Powles, Paul Liberator, Jennifer Anderson,

Antimicrobial Agents and Chemotherapy

1998

126

Characterization of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG): Antiparasitic activity of a PKG inhibitor☆

Carmen A. Diaz, John Allocco, Mary Ann Powles,

Molecular and Biochemical Parasitology

2005

97

Isolation and Structure Elucidation of Parnafungins, Antifungal Natural Products that Inhibit mRNA Polyadenylation

Craig A. Parish, Scott K. Smith, Kathleen Calati,

Journal of the American Chemical Society

2008

92

Broadening the Spectrum of β-Lactam Antibiotics through Inhibition of Signal Peptidase Type I

Alex G. Therien, Joann Huber, Kenneth E. Wilson,

Antimicrobial Agents and Chemotherapy

2012

77

Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes

Wen‐Lian Wu, Jinsong Hao, Martin S. Domalski,

ACS Medicinal Chemistry Letters

2016

44

MOLECULAR PHYLOGENY OF THE OTHER TISSUE COCCIDIA:<i>LANKESTERELLA</i>AND<i>CARYOSPORA</i>

JohnR. Barta, Donald S. Martin, Ramón A. Carreño,

Journal of Parasitology

2001

41

Design, Synthesis, and Evaluation of Novel and Selective G-protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists

Jason M. Cox, Hong D. Chu, Mariappan V. Chelliah,

ACS Medicinal Chemistry Letters

2016

32

MK-4815, a Potential New Oral Agent for Treatment of Malaria

Mary Ann Powles, John Allocco, Lai Yeung,

Antimicrobial Agents and Chemotherapy

2012

28

<i>In Vivo</i> Efficacy of Relebactam (MK-7655) in Combination with Imipenem-Cilastatin in Murine Infection Models

Mary Ann Powles, Andrew Galgoci, Andrew S. Misura,

Antimicrobial Agents and Chemotherapy

2018

26

Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects

Matthew Lombardo, Kate Bender, Clare London,

Bioorganic & Medicinal Chemistry Letters

2016

24

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