John Paul Smelko

Cross‐scale predictive modeling of <scp>CHO</scp> cell culture growth and metabolites using <scp>R</scp>aman spectroscopy and multivariate analysis

Brandon Berry, Justin Moretto, Thomas E. Matthews et al. · Biotechnology Progress · 2014 · 138 citations

Life Sciences, Biochemistry, Biotechnology +17

Closed loop control of lactate concentration in mammalian cell culture by Raman spectroscopy leads to improved cell density, viability, and biopharmaceutical protein production

Thomas E. Matthews, Brandon Berry, John Paul Smelko et al. · Biotechnology and Bioengineering · 2016 · 100 citations

Life Sciences, Biochemistry, Biotechnology +13

Performance of high intensity fed‐batch mammalian cell cultures in disposable bioreactor systems

John Paul Smelko, Kelly Wiltberger, Eric Francis Hickman et al. · Biotechnology Progress · 2011 · 46 citations

Engineering, Bioengineering, Biotechnology +17

Effects of solution environment on mammalian cell fermentation broth properties: Enhanced impurity removal and clarification performance

Matthew Westoby, James Chrostowski, Philippe de Vilmorin et al. · Biotechnology and Bioengineering · 2010 · 44 citations

Engineering, Bioengineering, Biotechnology +17

Glucose monitoring and adaptive feeding of mammalian cell culture in the presence of strong autofluorescence by near infrared Raman spectroscopy

Thomas E. Matthews, John Paul Smelko, Brandon Berry et al. · Biotechnology Progress · 2018 · 32 citations

Natural Sciences, Bioengineering, Biotechnology +17