Scott M. Irwin

Evaluation of a Mouse Model of Necrotic Granuloma Formation Using C3HeB/FeJ Mice for Testing of Drugs against Mycobacterium tuberculosis

Emily Driver, Gavin J. Ryan, Donald R. Hoff et al. · Antimicrobial Agents and Chemotherapy · 2012 · 274 citations

Veterinary Medicine, Infectious Diseases, Pharmacology +14

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with <i>Mycobacterium tuberculosis</i>

Scott M. Irwin, Emily Driver, Edward Lyon et al. · Disease Models & Mechanisms · 2015 · 189 citations · Full text

Veterinary Medicine, Infectious Diseases, Pathobiology +17

Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in <i>Mycobacterium tuberculosis</i> Infected C3HeB/FeJ Mice

Scott M. Irwin, Brendan Prideaux, Edward Lyon et al. · ACS Infectious Diseases · 2016 · 155 citations · Full text

Medicine, Infectious Diseases, Pharmacology +15

Limited Activity of Clofazimine as a Single Drug in a Mouse Model of Tuberculosis Exhibiting Caseous Necrotic Granulomas

Scott M. Irwin, Veronica Gruppo, Elizabeth J. Brooks et al. · Antimicrobial Agents and Chemotherapy · 2014 · 115 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +14

Phenotypic Definition of Effector and Memory T-Lymphocyte Subsets in Mice Chronically Infected with<i>Mycobacterium tuberculosis</i>

Marcela Henao‐Tamayo, Diane Ordway, Scott M. Irwin et al. · Clinical and Vaccine Immunology · 2010 · 111 citations · Full text

Life Sciences, Immunology, Microbiology +17