Larissa L Dougherty

RheoScale: A tool to aggregate and quantify experimentally determined substitution outcomes for multiple variants at individual protein positions

Abby M. Hodges, Aron W. Fenton, Larissa L Dougherty et al. · Human Mutation · 2018 · 32 citations

Life Sciences, Bioinformatics, Molecular Biology +14

Rheostat functional outcomes occur when substitutions are introduced at nonconserved positions that diverge with speciation

Liskin Swint‐Kruse, Tyler A. Martin, Braelyn M. Page et al. · Protein Science · 2021 · 26 citations · Full text

Life Sciences, Biology, Evolutionary Biology +15

Identification of biochemically neutral positions in liver pyruvate kinase

Tyler A. Martin, Tiffany Wu, Qingling Tang et al. · Proteins Structure Function and Bioinformatics · 2020 · 22 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

PYK-SubstitutionOME: an integrated database containing allosteric coupling, ligand affinity and mutational, structural, pathological, bioinformatic and computational information about pyruvate kinase isozymes

Liskin Swint‐Kruse, Larissa L Dougherty, Braelyn M. Page et al. · Database · 2023 · 10 citations · Full text

Life Sciences, Biochemistry, Bioinformatics +13