Hellmuth R. Hinz

Complete growth inhibition of human cancer xenografts in nude mice by treatment with 20-(S)-camptothecin.

B C Giovanella, Hellmuth R. Hinz, Anthony J. Kozielski et al. · PubMed · 1991 · 178 citations

Medicine, Oncology, Pharmacology +14

Complete inhibition of growth followed by death of human malignant melanoma cells in vitro and regression of human melanoma xenografts in immunodeficient mice induced by camptothecins.

Panayotis Pantazis, Hellmuth R. Hinz, John Mendoza et al. · PubMed · 1992 · 85 citations

Medicine, Oncology, Pharmacology +13

Regression of human breast carcinoma tumors in immunodeficient mice treated with 9-nitrocamptothecin: differential response of nontumorigenic and tumorigenic human breast cells in vitro.

Panayotis Pantazis, Janet Early, Anthony J. Kozielski et al. · PubMed · 1993 · 67 citations

Medicine, Oncology, Pharmacology +13

Camptothecin and its derivatives induce expression of the c-jun protooncogene in human myeloid leukemia cells.

Surender Kharbanda, Eric H. Rubin, Hisato Gunji et al. · PubMed · 1991 · 65 citations

Medicine, Oncology, Pharmacology +12

Camptothecin derivatives induce regression of human ovarian carcinomas grown in nude mice and distinguish between non‐tumorigenic and tumorigenic cells <i>in vitro</i>

Panayotis Pantazis, Anthony J. Kozielski, John Mendoza et al. · International Journal of Cancer · 1993 · 59 citations

Medicine, Oncology, Pharmacology +13