Jana De Vrieze

The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera

Raveen Rathnasinghe, Sonia Jangra, Anastasija Čupić et al. · medRxiv · 2021 · 137 citations · Full text

Veterinary Medicine, Infectious Diseases, Pathobiology +17

Efficient Innate Immune Killing of Cancer Cells Triggered by Cell‐Surface Anchoring of Multivalent Antibody‐Recruiting Polymers

Annemiek Uvyn, Ruben De Coen, Mandy Gruijs et al. · Angewandte Chemie International Edition · 2019 · 71 citations · Full text

Pharmacy, Immunology, Oncology +17

Sterilizing Immunity against SARS‐CoV‐2 Infection in Mice by a Single‐Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist‐Adjuvanted Recombinant Spike Protein Vaccine**

Sonia Jangra, Jana De Vrieze, Angela Choi et al. · Angewandte Chemie International Edition · 2021 · 69 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune Modulators

Anne Huppertsberg, Leonard Kaps, Zifu Zhong et al. · Journal of the American Chemical Society · 2021 · 66 citations · Full text

Pharmacy, Immunology, Pharmacology +17

Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer–Lipid Amphiphile Conjugates of Small‐Molecule TLR7/8 Agonists

Jana De Vrieze, Benoit Louage, Kim Deswarte et al. · Angewandte Chemie International Edition · 2019 · 64 citations

Life Sciences, Immunology, Medicinal Chemistry +17