Patrice Herait

Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer

David Cunningham, Seppo Pyrhönen, R.D. James et al. · The Lancet · 1998 · 1.3K citations

Gastrointestinal Oncology, Medicine, Cancer Management +6

Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer

Philippe Rougier, Eric Van Cutsem, Emilio Bajetta et al. · The Lancet · 1998 · 992 citations

Gastrointestinal Oncology, Medicine, Colorectal Cancer +8

Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy.

Philippe Rougier, R. Bugat, Jean‐Yves Douillard et al. · Journal of Clinical Oncology · 1997 · 429 citations

Bromodomain inhibitor OTX015 in patients with acute leukaemia: a dose-escalation, phase 1 study

Céline Berthon, Emmanuel Raffoux, Xavier Thomas et al. · The Lancet Haematology · 2016 · 425 citations

Hematological Malignancy, Translational Medicine, Acute Leukaemia +14

Bromodomain inhibitor OTX015 in patients with lymphoma or multiple myeloma: a dose-escalation, open-label, pharmacokinetic, phase 1 study

Sandy Amorim, Anastasios Stathis, Mary Gleeson et al. · The Lancet Haematology · 2016 · 420 citations

Hematological Malignancy, Lymphoid Neoplasia, Translational Medicine +9