Isabelle Guay

Tomatidine acts in synergy with aminoglycoside antibiotics against multiresistant Staphylococcus aureus and prevents virulence gene expression

Gabriel Mitchell, M. Lafrance, Simon Boulanger et al. · Journal of Antimicrobial Chemotherapy · 2011 · 106 citations · Full text

Medicine, Pharmacology, Veterinary Microbiology +17

Tomatidine Is a Lead Antibiotic Molecule That Targets Staphylococcus aureus ATP Synthase Subunit C

Maxime Lamontagne Boulet, Charles Isabelle, Isabelle Guay et al. · Antimicrobial Agents and Chemotherapy · 2018 · 83 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Unraveling the structure–activity relationship of tomatidine, a steroid alkaloid with unique antibiotic properties against persistent forms of Staphylococcus aureus

Félix Chagnon, Isabelle Guay, Marc‐André Bonin et al. · European Journal of Medicinal Chemistry · 2014 · 51 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Tomatidine and analog FC04–100 possess bactericidal activities against Listeria, Bacillus and Staphylococcus spp

Isabelle Guay, Simon Boulanger, Charles Isabelle et al. · BMC Pharmacology and Toxicology · 2018 · 48 citations · Full text

Medicine, Microbiology, Pharmacology +15

Bactericidal Activity of the Bacterial ATP Synthase Inhibitor Tomatidine and the Combination of Tomatidine and Aminoglycoside Against Persistent and Virulent Forms of Staphylococcus aureus

Jean-Philippe Langlois, Guillaume Millette, Isabelle Guay et al. · Frontiers in Microbiology · 2020 · 24 citations · Full text

Medicine, Infectious Diseases, Pharmacology +15