František Hubálek

Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders

Claudia Binda, Paige Newton‐Vinson, František Hubálek et al. · Nature Structural Biology · 2001 · 634 citations

Medicine, Medicinal Chemistry, Pharmacology +15

An ingestible self-orienting system for oral delivery of macromolecules

Alex Abramson, Ester Caffarel–Salvador, Minsoo Khang et al. · Science · 2019 · 436 citations · Full text

Pharmacy, Bioengineering, Pharmaceutics +11

Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures

Claudia Binda, Min Li, František Hubálek et al. · Proceedings of the National Academy of Sciences · 2003 · 398 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Demonstration of Isoleucine 199 as a Structural Determinant for the Selective Inhibition of Human Monoamine Oxidase B by Specific Reversible Inhibitors

František Hubálek, Claudia Binda, Ashraf Khalil et al. · Journal of Biological Chemistry · 2005 · 231 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Crystal Structures of Monoamine Oxidase B in Complex with Four Inhibitors of the<i>N</i>-Propargylaminoindan Class

Claudia Binda, František Hubálek, Min Li et al. · Journal of Medicinal Chemistry · 2004 · 214 citations

Life Sciences, Biochemistry, Pharmacology +17