Jonathan B. Ruddle

Human TUBB3 Mutations Perturb Microtubule Dynamics, Kinesin Interactions, and Axon Guidance

Max A. Tischfield, Hagit Baris, Chen Wu et al. · Cell · 2010 · 589 citations · Full text

Axon Guidance, Protein Function, Molecular Biology +8

Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

Jamie E. Craig, Xikun Han, Ayub Qassim et al. · Nature Genetics · 2020 · 339 citations · Full text

Genome-wide Association Study, Disease Susceptibility, Medicine +12

Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity

Tomokazu Souma, Stuart W. Tompson, Benjamin R. Thomson et al. · Journal of Clinical Investigation · 2016 · 286 citations · Full text

Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma

Puya Gharahkhani, Kathryn P. Burdon, Rhys Fogarty et al. · Nature Genetics · 2014 · 228 citations · Full text

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

Stuart MacGregor, Jue‐Sheng Ong, Jiyuan An et al. · Nature Genetics · 2018 · 219 citations · Full text

Genome-wide Association Study, Transcriptional Regulation, Systems Biology +8