Wayne Yu

A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

Joyce E. Ohm, Kelly M. McGarvey, Xiaobing Yu et al. · Nature Genetics · 2007 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Multiple-laboratory comparison of microarray platforms

Rafael A. Irizarry, Daniel Warren, Forrest Spencer et al. · Nature Methods · 2005 · 883 citations

Life Sciences, Bioinformatics, Molecular Biology +13

Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency-Associated Genes

Prashant Mali, Bin-Kuan Chou, Jonathan Yen et al. · Stem Cells · 2010 · 416 citations · Full text

Life Sciences, Cell Biology, Genetics +15

Comparing the DNA Hypermethylome with Gene Mutations in Human Colorectal Cancer

Kornel E. Schuebel, Wei Chen, Leslie Cope et al. · PLoS Genetics · 2007 · 348 citations · Full text

Medicine, Genetics, Oncology +17

MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3 #

Florin M. Selaru, Alexandru Olaru, Takatsugu Kan et al. · Hepatology · 2009 · 296 citations

Medicine, Cancer Biology, Oncology +14