Karthik Murugan

CRISPR-Cas12a has widespread off-target and dsDNA-nicking effects

Karthik Murugan, Arun S. Seetharam, Andrew Severin et al. · Journal of Biological Chemistry · 2020 · 160 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

High-frequency random DNA insertions upon co-delivery of CRISPR-Cas9 ribonucleoprotein and selectable marker plasmid in rice

Raviraj Banakar, Alan L. Eggenberger, Keunsub Lee et al. · Scientific Reports · 2019 · 112 citations · Full text

Life Sciences, Genetics, Plant Sciences +17

Comparative analysis of CRISPR off-target discovery tools following ex vivo editing of CD34+ hematopoietic stem and progenitor cells

M. Kyle Cromer, Kiran R. Majeti, Garrett R. Rettig et al. · Molecular Therapy · 2023 · 39 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Green synthesis of a redox-active riboflavin-integrated Ni-MOF and its versatile electrocatalytic applications towards oxygen evolution and reduction, and HMF oxidation reactions

Pandiaraj Sekar, P. Vasanthakumar, Shanmugam Senthil Kumar et al. · Green Chemistry · 2022 · 33 citations

Natural Sciences, Chemistry, Materials Science +17

Systematic<i>in vitro</i>specificity profiling reveals nicking defects in natural and engineered CRISPR–Cas9 variants

Karthik Murugan, Shravanti K. Suresh, Arun S. Seetharam et al. · Nucleic Acids Research · 2021 · 24 citations · Full text

Life Sciences, Biotechnology, Genetics +13