Maria V Abrenica

Asp-to-Asn Substitution at the First Position of the DxD TOPRIM Motif of Recombinant Bacterial Topoisomerase I Is Extremely Lethal to E. coli

Bokun Cheng, Thirunavukkarasu Annamalai, Elena P. Sorokin et al. · Journal of Molecular Biology · 2008 · 37 citations · Full text

Life Sciences, Microbiology, Molecular Biology +6

Inhibition of Mg 2+ binding and DNA religation by bacterial topoisomerase I via introduction of an additional positive charge into the active site region

Elena P. Sorokin, Bokun Cheng, Siddarth Rathi et al. · Nucleic Acids Research · 2008 · 28 citations · Full text

Life Sciences, Microbiology, Molecular Biology +13

The DNA relaxation activity and covalent complex accumulation of Mycobacterium tuberculosis topoisomerase I can be assayed in Escherichia coli: application for identification of potential FRET-dye labeling sites

Gagandeep Narula, Jennifer Becker, Bokun Cheng et al. · BMC Biochemistry · 2010 · 16 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15