Linda J Driggers

Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells.

Pamela L. Rice, Jennifer Kelloff, Holly Sullivan et al. · PubMed · 2003 · 101 citations

Proteasome-dependent Degradation, Chemoprevention Strategy, Pathology +16

Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites.

P. Rice, Robert J. Goldberg, Evan C. Ray et al. · PubMed · 2001 · 83 citations

Chemoprevention Strategy, Apoptosis, Cell Death +18

Inhibition of Extracellular-signal Regulated Kinases 1/2 Is Required for Apoptosis of Human Colon Cancer Cells <b> <i>In vitro</i> </b> by Sulindac Metabolites

Pamela L. Rice, K. Beard, Linda J Driggers et al. · Cancer Research · 2004 · 39 citations · Full text

Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells.

Pamela L. Rice, Michele N. Washington, Shea Schleman et al. · PubMed · 2003 · 35 citations

Tumor Biology, Oncology, Chemoprevention Strategy +14