Dereck D. Amakye

A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors

Jordi Rodón, Hussein Tawbi, Anne Thomas et al. · Clinical Cancer Research · 2014 · 228 citations · Full text

Safety, tolerability, pharmacokinetics and pharmacodynamics of the oral cyclin-dependent kinase inhibitor AZD5438 when administered at intermittent and continuous dosing schedules in patients with advanced solid tumours

David S. Boss, Gary K. Schwartz, Mark R. Middleton et al. · Annals of Oncology · 2009 · 63 citations

Oncology, Pharmacology, Advanced Solid Tumours +5

A Prototypical Process for Creating Evidentiary Standards for Biomarkers and Diagnostics

C. Anthony Altar, Dereck D. Amakye, D Bounos et al. · Clinical Pharmacology & Therapeutics · 2007 · 61 citations

A Five-Gene Hedgehog Signature Developed as a Patient Preselection Tool for Hedgehog Inhibitor Therapy in Medulloblastoma

Yaping Shou, Douglas Robinson, Dereck D. Amakye et al. · Clinical Cancer Research · 2014 · 57 citations

Improved Efficacy Of Combination Of JAK2 and Hedgehog Inhibitors In Myelofibrosis

Neha Bhagwat, Matthew D. Keller, Raajit K. Rampal et al. · Blood · 2013 · 53 citations