Francisco Tomé

Structures of β-klotho reveal a ‘zip code’-like mechanism for endocrine FGF signalling

Sangwon Lee, Jungyuen Choi, Jyotidarsini Mohanty et al. · Nature · 2018 · 222 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +9

The Selectivity of Receptor Tyrosine Kinase Signaling Is Controlled by a Secondary SH2 Domain Binding Site

Jae Hyun Bae, Erin D. Lew, Satoru Yuzawa et al. · Cell · 2009 · 158 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand–receptor interactions

Andrey V. Reshetnyak, Phillip B. Murray, Xiarong Shi et al. · Proceedings of the National Academy of Sciences · 2015 · 153 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis

Veraragavan P. Eswarakumar, Ferruh Özcan, Erin D. Lew et al. · Proceedings of the National Academy of Sciences · 2006 · 113 citations · Full text

Dentistry, Developmental Biology, Genetics +17

Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells

Jae Hyun Bae, Titus J. Boggon, Francisco Tomé et al. · Proceedings of the National Academy of Sciences · 2010 · 80 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16