Majed Al Fayi

Thymoquinone and curcumin combination protects cisplatin-induced kidney injury, nephrotoxicity by attenuating NFκB, KIM-1 and ameliorating Nrf2/HO-1 signalling

Majed Al Fayi, Hassan M. Otifi, Mishari Alshyarba et al. · Journal of drug targeting · 2020 · 74 citations · Full text

Medicine, Pharmacology, Toxicology +15

FCX‐146, a potent allosteric inhibitor of Akt kinase in cancer cells: Lead optimization of the second‐generation arylidene indanone scaffold

Meenakshisundaram Balasubramaniam, Naga Rajiv Lakkaniga, Ayed A. Dera et al. · Biotechnology and Applied Biochemistry · 2020 · 27 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Indirubin-3-monoxime and thymoquinone exhibit synergistic efficacy as therapeutic combination in in-vitro and in-vivo models of Lung cancer

Ayed A. Dera, Prasanna Rajagopalan, Majed Al Fayi et al. · Archives of Pharmacal Research · 2020 · 26 citations

Medicine, Oncology, Pharmacology +6

Thymoquinone (Tq) protects necroptosis induced by autophagy/mitophagy‐dependent oxidative stress in human bronchial epithelial cells exposed to cigarette smoke extract (CSE)

Ayed A. Dera, Majed Al Fayi, Hassan M. Otifi et al. · Journal of Food Biochemistry · 2020 · 26 citations

Life Sciences, Cell Biology, Pharmacology +17

Thymoquinone inhibits IL‐7‐induced tumor progression and metastatic invasion in prostate cancer cells by attenuating matrix metalloproteinase activity and Akt/NF‐κB signaling

Mishari Alshyarba, Hassan M. Otifi, Majed Al Fayi et al. · Biotechnology and Applied Biochemistry · 2020 · 21 citations

Medicine, Oncology, Pharmacology +14