Alex Goldstein

The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant effects on cell proliferation and drug resistance

Jan S. Moreb, Deniz A. Uçar, Shuhong Han et al. · Chemico-Biological Interactions · 2011 · 203 citations

Life Sciences, Biochemistry, Pharmacology +9

Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors

Yan Chen, Jin-Yi Zhu, Kwon Ho Hong et al. · ACS Chemical Biology · 2017 · 95 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15

Inhibition of Retinoic Acid Biosynthesis by the Bisdichloroacetyldiamine WIN 18,446 Markedly Suppresses Spermatogenesis and Alters Retinoid Metabolism in Mice

Jisun Paik, Michael Haenisch, Charles Müller et al. · Journal of Biological Chemistry · 2014 · 89 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Pharmacological inhibition of ALDH1A enzymes suppresses weight gain in a mouse model of diet-induced obesity

Michael Haenisch, Piper M. Treuting, Thea Brabb et al. · Obesity Research & Clinical Practice · 2017 · 48 citations · Full text

Life Sciences, Biochemistry, Pharmacology +11

Protection of a Decapeptide from Proteolytic Cleavage by Lipidation and Self-Assembly into High-Axial-Ratio Microstructures:  A Kinetic and Structural Study

Kyujin C. Lee, Paul A. Carlson, Alex Goldstein et al. · Langmuir · 1999 · 40 citations

Life Sciences, Biochemistry, Biophysics +17