Tanya Coleman

AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family

Paul R. Gavine, Lorraine Mooney, Elaine Kilgour et al. · Cancer Research · 2012 · 499 citations

Medicine, Oncology, Pharmacology +16

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is N-demethylated by cytochromes P450 2D6, 1A2 and 3A4--implications for susceptibility to Parkinson's disease.

Tanya Coleman, S. W. Ellis, Ian Martin et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 96 citations

Medicine, Pharmacology, Toxicology +17

Induction of P-glycoprotein expression and function in human intestinal epithelial cells (T84)

Iain S. Haslam, Karen L. Jones, Tanya Coleman et al. · Biochemical Pharmacology · 2008 · 69 citations

Life Sciences, Immunology, Molecular Biology +9

Intestinal Ciprofloxacin Efflux: The Role of Breast Cancer Resistance Protein (ABCG2)

Iain S. Haslam, Jayne Wright, Derek O’Reilly et al. · Drug Metabolism and Disposition · 2011 · 63 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

The statin class of HMG-CoA reductase inhibitors demonstrate differential activation of the nuclear receptors PXR, CAR and FXR, as well as their downstream target genes

Katharine Howe, Faizah Sanat, Alfred E. Thumser et al. · Xenobiotica · 2011 · 61 citations

Life Sciences, Biochemistry, Pharmacology +14