Hitchings Gh

RELATIONSHIP BETWEEN METABOLIC FATES AND ANTITUMOR ACTIVITIES OF THIOPURINES.

Elion Gb, Shellie M. Callahan, Rundles Rw et al. · PubMed · 1963 · 117 citations

Medicinal Chemistry, Biochemistry, 6-Thiouric Acid +13

Species differences among dihydrofolate reductases as a basis for chemotherapy.

Hitchings Gh · PubMed · 1969 · 50 citations

Aldo-keto Reductase, Biochemistry, Medicine +5

Observations on the anticancer activity of 6-mercaptopurine.

Skipper He, Thomson, Elion Gb et al. · PubMed · 1954 · 49 citations

Tumor Biology, Medicinal Chemistry, Pharmaceutical Science +14

The effect of 8-azaguanine on the growth of carcinoma, sarcoma, osteogenic sarcoma, lymphosarcoma and melanoma in animals.

Kimihiko Sugiura, Hitchings Gh · PubMed · 1950 · 44 citations

Sarcoma R39, Oncology, Chemoprevention Strategy +14

Experimental, clinical, and metabolic studies of thiopurines.

Elion Eb, Callahan Sw, Hitchings Gh et al. · PubMed · 1962 · 32 citations

Metabolic Studies, Biochemistry, Medicine +6