Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs

Kevin Hadi, Xiaotong Yao, Julie M. Behr, +49

Cell

BioinformaticsChromatinGraph TheoryTumor HeterogeneityCancer Genome Graphs +11

Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

Daniel Butler, Christopher Mozsary, Cem Meydan, +76

Nature Communications

Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions

Daniel Butler, Christopher Mozsary, Cem Meydan, +49

Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer

Andrew Webster, Mathijs A. Sanders, Krupa R. Patel, +46

Nature

ChromatinGenome InstabilitySomatic VariantMedicineGenetics +6

Tracking and transforming neocortical progenitors by CRISPR/Cas9 gene targeting and <i>PiggyBac</i> transposase lineage labeling

Fuyi Chen, Joel Rosiene, Alicia Che, +2

Development

Molecular Evolution of Classic Hodgkin Lymphoma Revealed Through Whole-Genome Sequencing of Hodgkin and Reed Sternberg Cells

Francesco Maura, Bachisio Ziccheddu, Jenny Xiang, +29

Blood Cancer Discovery

System-wide transcriptome damage and tissue identity loss in COVID-19 patients

Jiwoon Park, Jonathan Foox, Tyler Hether, +45

Cell Reports Medicine

Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers

Jeremy Setton, Kevin Hadi, Zi-Ning Choo, +18

Nature

Most large structural variants in cancer genomes can be detected without long reads

Zi-Ning Choo, Julie M. Behr, Aditya Deshpande, +17

Nature Genetics

Structural variant evolution after telomere crisis

Sally M. Dewhurst, Xiaotong Yao, Joel Rosiene, +6

Nature Communications