Deborah L. Lewis

G-protein βγ-subunits activate the cardiac muscarinic K+-channel via phospholipase A2

Dong Hee Kim, Deborah L. Lewis, Linda Graziadei et al. · Nature · 1989 · 434 citations

Molecular Pharmacology, Cardiac Muscle, Molecular Physiology +13

A guanine nucleotide-binding protein mediates the inhibition of voltage-dependent calcium current by somatostatin in a pituitary cell line.

Deborah L. Lewis, Forrest F. Weight, Alberto Luini · Proceedings of the National Academy of Sciences · 1986 · 242 citations · Full text

Guanine Nucleotide-binding Protein, Cellular Physiology, Pituitary Gland +21

SR 141716A Acts as an Inverse Agonist to Increase Neuronal Voltage-Dependent Ca2+ Currents by Reversal of Tonic CB1 Cannabinoid Receptor Activity

Xianghua Pan, Stephen R. Ikeda, Deborah L. Lewis · Molecular Pharmacology · 1998 · 181 citations

N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) Interaction with LYS 3.28(192) Is Crucial for Its Inverse Agonism at the Cannabinoid CB1 Receptor

Dow P. Hurst, Diane L. Lynch, Judy Barnett‐Norris et al. · Molecular Pharmacology · 2002 · 159 citations

The CB1 Cannabinoid Receptor Can Sequester G-Proteins, Making Them Unavailable to Couple to Other Receptors

Clemente Vásquez, Deborah L. Lewis · Journal of Neuroscience · 1999 · 148 citations · Full text