Rapid, high-yield production in plants of individualized idiotype vaccines for non-Hodgkin's lymphoma

Maurizio Bendandi, Sylvestre Marillonnet, Romy Kandzia, +15

Annals of Oncology

VaccinationMolecular PharmingImmunologyBiotechnologyTherapeutic Vaccine +6

Clinical Benefit Associated With Idiotypic Vaccination in Patients With Follicular Lymphoma

Susana Inogés, Mercedes Rodrı́guez-Calvillo, Natalia Zabalegui, +13

JNCI Journal of the National Cancer Institute

CD28 Aptamers as Powerful Immune Response Modulators

Fernando Pastor, Mario Martínez Soldevilla, Helena Villanueva, +8

Molecular Therapy — Nucleic Acids

2-fluoro-RNA oligonucleotide CD40 targeted aptamers for the control of B lymphoma and bone-marrow aplasia

Mario Martínez Soldevilla, Helena Villanueva, Maurizio Bendandi, +3

Biomaterials

Hematological MalignancyLymphoid NeoplasiaRadiation OncologyMedicineMalignant Blood Disorder +10

MRP1-CD28 bi-specific oligonucleotide aptamers: target costimulation to drug-resistant melanoma cancer stem cells

Mario Martínez Soldevilla, Helena Villanueva, Noëlia Casares, +5

Oncotarget

ImmunologyImmunoeditingImmunotherapyTumor BiologySynthetic Immunology +15

Targeting inhibition of Foxp3 by a CD28 2′-Fluro oligonucleotide aptamer conjugated to P60-peptide enhances active cancer immunotherapy

Teresa Lozano, Mario Martínez Soldevilla, Noëlia Casares, +4

Biomaterials

Cancer ImmunosurveillanceImmunologyTumor TargetingImmunotherapyMedicine +3

In Silico Aptamer Docking Studies: From a Retrospective Validation to a Prospective Case Study'TIM3 Aptamers Binding

Obdulia Rabal, Fernando Pastor, Helena Villanueva, +3

Molecular Therapy — Nucleic Acids

Identification of TIM3 2′-fluoro oligonucleotide aptamer by HT-SELEX for cancer immunotherapy

Sandra Hervás‐Stubbs, Mario Martínez Soldevilla, Helena Villanueva, +3

Oncotarget

ICOS Costimulation at the Tumor Site in Combination with CTLA-4 Blockade Therapy Elicits Strong Tumor Immunity

Mario Martínez Soldevilla, Helena Villanueva, Daniel Meraviglia-Crivelli, +10

Molecular Therapy

Identification of LAG3 high affinity aptamers by HT-SELEX and Conserved Motif Accumulation (CMA)

Mario Martínez Soldevilla, Sandra Hervás, Helena Villanueva, +8

PLoS ONE

Lag3 Receptor BelongsStructural BioinformaticsBiomolecular Structure PredictionImmunologyMolecular Biology +18