Bactericidal mode of action of bedaquiline

Kiel Hards, Jennifer Robson, Michael Berney, +5

Journal of Antimicrobial Chemotherapy

Exploiting the synthetic lethality between terminal respiratory oxidases to kill <i>Mycobacterium tuberculosis</i> and clear host infection

Nitin Pal Kalia, Erik Hasenoehrl, Nurlilah B. Ab Rahman, +9

Proceedings of the National Academy of Sciences

A soil actinobacterium scavenges atmospheric H ₂ using two membrane-associated, oxygen-dependent [NiFe] hydrogenases

Chris Greening, Michael Berney, Kiel Hards, +2

Proceedings of the National Academy of Sciences

EngineeringHydrogenase ExpressionMicrobial PhysiologyRedox BiologyAnaerobic Culturing +14

Persistence of the dominant soil phylum <i>Acidobacteria</i> by trace gas scavenging

Chris Greening, Carlo R. Carere, Rowena Rushton-Green, +6

Proceedings of the National Academy of Sciences

EngineeringStationary PhaseSoil BiodiversityTrace Gas ScavengingBiological Carbon Fixation +15

Mixotrophy drives niche expansion of verrucomicrobial methanotrophs

Carlo R. Carere, Kiel Hards, Karen M. Houghton, +9

The ISME Journal

BiologyMicrobial DiversityBiogeochemistryEngineeringBioenergetics +12

Ionophoric effects of the antitubercular drug bedaquiline

Kiel Hards, Duncan G. G. McMillan, Lici A. Schurig-Briccio, +4

Proceedings of the National Academy of Sciences

Pyrazolo[1,5-<i>a</i>]pyridine Inhibitor of the Respiratory Cytochrome <i>bcc</i> Complex for the Treatment of Drug-Resistant Tuberculosis

Xiaoyun Lu, Zoe C. Williams, Kiel Hards, +15

ACS Infectious Diseases

Essentiality of Succinate Dehydrogenase in Mycobacterium smegmatis and Its Role in the Generation of the Membrane Potential Under Hypoxia

Ildikó Pécsi, Kiel Hards, Nandula Ekanayaka, +4

mBio

Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant <i>Mycobacterium tuberculosis</i>

Bei Shi Lee, Kiel Hards, Curtis A. Engelhart, +18

EMBO Molecular Medicine

Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering

Brendon M. Lee, Liam K. Harold, Deepak V. Almeida, +15

PLoS Pathogens

Molecular BiologyAntimicrobial ChemotherapyAntibiotic ResistanceDrug ResistanceM. Tuberculosis +14