Towards molecular farming in the future: using plant‐cell‐suspension cultures as bioreactors

R. Fischer, Neil Emans, Flora Schuster, +2

Biotechnology and Applied Biochemistry

EngineeringMolecular PharmingSecondary MetabolitesMolecular FarmingBiosynthesis +15

Analysis of single-chain antibody production in Pichia pastoris using on-line methanol control in fed-batch and mixed-feed fermentations.

Stephan Hellwig, Frank Emde, Nicole Raven, +3

PubMed

EngineeringAvailable Methanol SensorSingle-chain Antibody ProductionBiosynthesisBioenergetics +17

Analysis of single‐chain antibody production in <i>Pichia pastoris</i> using on‐line methanol control in fed‐batch and mixed‐feed fermentations

Stephan Hellwig, Frank Emde, Nicole Raven, +3

Biotechnology and Bioengineering

EngineeringAvailable Methanol SensorBiosynthesisOn‐line Methanol ControlBiochemical Engineering +15

From gene to harvest: insights into upstream process development for the <scp>GMP</scp> production of a monoclonal antibody in transgenic tobacco plants

M. Sack, Thomas W. Rademacher, Holger Spiegel, +5

Plant Biotechnology Journal

Optimal nitrogen supply as a key to increased and sustained production of a monoclonal full‐size antibody in BY‐2 suspension culture

Tanja Holland, M. Sack, T. W. Rademacher, +5

Biotechnology and Bioengineering

Plant PhysiologyEngineeringBy‐2 Suspension CultureImmunologyCell Culture +21

Necessity of a two-stage process for the production of azadirachtin-related limonoids in suspension cultures of Azadirachta indica

Keyur Raval, Stephan Hellwig, Gunjan Prakash, +3

Journal of Bioscience and Bioengineering

BiosynthesisBotanyAzadirachtin-related LimonoidsPlant Cell CultureAzadirachta Indica +3

Towards molecular farming in the future: <i>Pichia pastoris</i>‐based production of single‐chain antibody fragments

Rainer Fischer, Jürgen Drossard, Neil Emans, +2

Biotechnology and Applied Biochemistry

EngineeringSingle‐chain Antibody FragmentsMolecular FarmingBiosynthesisBiochemical Engineering +16

Towards industrial usefulness – cryo-cell-banking of transgenic BY-2 cell cultures

Kathrin Schmale, Thomas W. Rademacher, Rainer Fischer, +1

Journal of Biotechnology

Cell FactoriesBiomanufacturingEngineeringMedicineBiotechnology +5

Increase of calnexin gene dosage boosts the secretion of heterologous proteins by<i>Hansenula polymorpha</i>

Jens Klabunde, Sebastian Kleebank, Michael Piontek, +3

FEMS Yeast Research

Protein SecretionMolecular BiologyQuality Control MechanismHpcne1 Expression PlasmidsBiosynthesis +16

Improvement of a fermentation process for the production of two PfAMA1-DiCo-based malaria vaccine candidates in Pichia pastoris

Robin Kastilan, Alexander Boes, Holger Spiegel, +6

Scientific Reports