Clare D. Hammond

Design and Optimization of Pyrazinecarboxamide-Based Inhibitors of Diacylglycerol Acyltransferase 1 (DGAT1) Leading to a Clinical Candidate Dimethylpyrazinecarboxamide Phenylcyclohexylacetic Acid (AZD7687)

Jonas G. Barlind, Udo Bauer, Alan M. Birch et al. · Journal of Medicinal Chemistry · 2012 · 36 citations · Full text

Pharmaceutical Science, Candidate Drug, Pyrazinecarboxamide Dgat1 Inhibitors +17

Indazole-6-phenylcyclopropylcarboxylic Acids as Selective GPR120 Agonists with in Vivo Efficacy

William McCoull, Andrew Bailey, Peter Barton et al. · Journal of Medicinal Chemistry · 2017 · 33 citations · Full text

Molecular Pharmacology, Gpr120 Agonists, Gpr120 Potency +12

Kinetics of the time-dependent inactivation of CYP2D6 in cryopreserved human hepatocytes by methylenedioxymethamphetamine (MDMA)

Linh Van, John G. Swales, Clare D. Hammond et al. · European Journal of Pharmaceutical Sciences · 2007 · 22 citations

Biochemistry, Medicine, Liver Physiology +8

Prolonged Inhibition of Glycogen Phosphorylase in Livers of Zucker Diabetic Fatty Rats Models Human Glycogen Storage Diseases

Eike Floettmann, Laraine Gregory, Joanne Teague et al. · Toxicologic Pathology · 2010 · 19 citations

Fatty Liver Disease, Insulin Signaling, Prolonged Inhibition +18