Ne N. Wu

The E3 ubiquitin ligase MARCH2 protects against myocardial ischemia-reperfusion injury through inhibiting pyroptosis via negative regulation of PGAM5/MAVS/NLRP3 axis

Shuolin Liu, Yaguang Bi, Tianting Han et al. · Cell Discovery · 2024 · 74 citations · Full text

Inflammasome Activation, Apoptosis, Immunology +23

CD74 ablation rescues type 2 diabetes mellitus-induced cardiac remodeling and contractile dysfunction through pyroptosis-evoked regulation of ferroptosis

Lin Chen, Zhiqiang Yin, Xing Qin et al. · Pharmacological Research · 2022 · 66 citations

Cardiomyopathy, Signal Transduction, Pyroptosis-evoked Regulation +9

Double knockout of Akt2 and AMPK accentuates high fat diet-induced cardiac anomalies through a cGAS-STING-mediated mechanism

Yan Gong, Guangwei Li, Jun Tao et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2020 · 64 citations

Obesity, Metabolic Syndrome, Cardiomyopathy +12

TBC1D15-Drp1 interaction-mediated mitochondrial homeostasis confers cardioprotection against myocardial ischemia/reperfusion injury

Shiqun Sun, Wenjun Yu, Haixia Xu et al. · Metabolism · 2022 · 61 citations

Heart Failure, Molecular Physiology, Mitochondrial Function +7

Site-specific ubiquitination of VDAC1 restricts its oligomerization and mitochondrial DNA release in liver fibrosis

Ne N. Wu, Lifeng Wang, Lu Wang et al. · Experimental & Molecular Medicine · 2023 · 48 citations · Full text