Sanda Alexandrescu

Mechanisms and therapeutic implications of hypermutation in gliomas

Mehdi Touat, Yvonne Y. Li, Adam N. Boynton et al. · Nature · 2020 · 661 citations · Full text

Neuro-oncology, Medicine, Therapeutic Implications +5

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG

Jamie N. Anastas, Barry M. Zee, Jay H. Kalin et al. · Cancer Cell · 2019 · 180 citations · Full text

Histone Modifications, Chromatin, Re-programing Chromatin +10

The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

Ilon Liu, Li Jiang, Erik Samuelsson et al. · Nature Genetics · 2022 · 173 citations · Full text

Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma

Johannes Gojo, Bernhard Englinger, Li Jiang et al. · Cancer Cell · 2020 · 153 citations · Full text

Cell Lineage, Developmental Biology, Single Cell Sequencing +10

ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition

Paul G. Kemps, Jennifer Picarsic, Benjamin H. Durham et al. · Blood · 2021 · 144 citations · Full text