C5a Negatively Regulates Toll-like Receptor 4-Induced Immune Responses

Heiko Hawlisch, Yasmine Belkaid, Ralf Baelder, +3

Immunity

InflammationToll-like ReceptorsMolecular ImmunologyInnate Immune SystemImmunology +3

Complement C5 Mediates Experimental Tubulointerstitial Fibrosis

Peter Boor, Andrzej Konieczny, Luigi Villa, +12

Journal of the American Society of Nephrology

Renal PathologyImmunologyRenal InflammationPathologyExperimental Pathology +25

C5a Initiates the Inflammatory Cascade in Immune Complex Peritonitis

Jeanne Godau, Tanja Heller, Heiko Hawlisch, +11

The Journal of Immunology

InflammationComplement SystemInflammatory DiseaseAutoimmune DiseaseImmune Effector Functions +13

Complement 5a Receptor Inhibition Improves Renal Allograft Survival

Faikah Gueler, Song Rong, Wilfried Gwinner, +10

Journal of the American Society of Nephrology

ImmunologyTransplantation MedicineRenal InflammationImmunotherapyInflammation +17

C5a Mutants Are Potent Antagonists of the C5a Receptor (CD88) and of C5L2

Magnus Otto, Heiko Hawlisch, Peter N. Monk, +4

Journal of Biological Chemistry

C5a Receptor Targeting in Neointima Formation After Arterial Injury in Atherosclerosis-Prone Mice

Erdenechimeg Shagdarsuren, Kiril Bidzhekov, Sebastian F. Mause, +6

Circulation

Peptidomimetic C5a receptor antagonists with hydrophobic substitutions at the C-terminus: Increased receptor specificity and in vivo activity

Karsten Schnatbaum, Elsa Locardi, Dirk Scharn, +4

Bioorganic & Medicinal Chemistry Letters

Vivo ActivityBiochemistryFunctional SelectivityReceptor SpecificityMedicine +8

Site-Specific Anti-C3a Receptor Single-Chain Antibodies Selected by Differential Panning on Cellulose Sheets

Heiko Hawlisch, Melanie Müller, Ronald Frank, +3

Analytical Biochemistry

Cellulose SheetsImmunocytochemical TechniqueAutoimmune DiseaseGlycobiologyImmunology +9

Site-Directed C3a Receptor Antibodies from Phage Display Libraries

Heiko Hawlisch, Ronald Frank, Meike Hennecke, +7

The Journal of Immunology

Phage Display LibrariesScfvs BoundImmunologyMaltose Binding ProteinAntibody Engineering +14

Guinea pig C3 specific rabbit single chain Fv antibodies from bone marrow, spleen and blood derived phage libraries

Heiko Hawlisch, Andreas Meyer zu Vilsendorf, Wilfried Bautsch, +2

Journal of Immunological Methods

Phage LibrariesLaboratory ImmunologyHumoral ResponseImmunologyPathology +6