Elizabeth McWhinnie

Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells

Vadim Iourgenko, Wenjun Zhang, Craig Mickanin et al. · Proceedings of the National Academy of Sciences · 2003 · 370 citations · Full text

Molecular Biology, Gene Regulatory Network, Unbiased Method +17

Integrating high-content screening and ligand-target prediction to identify mechanism of action

Daniel Young, Andreas Bender, J.D. Hoyt et al. · Nature Chemical Biology · 2007 · 350 citations · Full text

Molecular Docking, Medicinal Chemistry, Virtual Screening +13

Activation of cAMP Response Element-Mediated Gene Expression by Regulated Nuclear Transport of TORC Proteins

Mark Bittinger, Elizabeth McWhinnie, Jodi Meltzer et al. · Current Biology · 2004 · 228 citations · Full text

Signal Transduction, Natural Sciences, Torc Proteins +8

Deubiquitinase FAM/USP9X Interacts with the E3 Ubiquitin Ligase SMURF1 Protein and Protects It from Ligase Activity-dependent Self-degradation

Yang Xie, Monika Avello, Markus Schirle et al. · Journal of Biological Chemistry · 2012 · 110 citations · Full text

Reductive Stress, Protein Function, Deubiquitinase Fam/usp9x +15

DNA sequencing and CRISPR-Cas9 gene editing for target validation in mammalian cells

Yegor D. Smurnyy, Mi Cai, Hua Wu et al. · Nature Chemical Biology · 2014 · 93 citations

Dna Sequencing, Off-target Effect, Genetics +9