Michel Hugues

Apamin as a selective blocker of the calcium-dependent potassium channel in neuroblastoma cells: voltage-clamp and biochemical characterization of the toxin receptor.

Michel Hugues, Georges Romey, D Duval et al. · Proceedings of the National Academy of Sciences · 1982 · 348 citations

Medicine, Neurobiology, Pharmacology +17

Purification and pharmacological properties of eight sea anemone toxins from Anemonia sulcata, Anthopleura xanthogrammica, Stoichactis giganteus and Actinodendron plumosum

Hugues Schweitz, Jean Pierre Vincent, Jacques Barhanin et al. · Biochemistry · 1981 · 136 citations

Pharmacy, Pharmacology, Toxicology +10

Preparation of a pure monoiodo derivative of the bee venom neurotoxin apamin and its binding properties to rat brain synaptosomes.

Michel Hugues, D Duval, Patrick Kitabgi et al. · Journal of Biological Chemistry · 1982 · 125 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Expression of apamin receptor in muscles of patients with myotonic muscular dystrophy

Jean‐François Renaud, Claude Desnuelle, Heidy Schmid‐Antomarchi et al. · Nature · 1986 · 122 citations

Medicine, Neurology, Neuromuscular Disorders +10

Leiurotoxin I (scyllatoxin), a peptide ligand for Ca2(+)-activated K+ channels. Chemical synthesis, radiolabeling, and receptor characterization.

Patrick Auguste, Michel Hugues, B Gravé et al. · Journal of Biological Chemistry · 1990 · 121 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +15