Sofia Guzzetti

Preclinical Characterization of AZD9574, a Blood–Brain Barrier Penetrant Inhibitor of PARP1

Anna D. Staniszewska, Domenic Pilger, Sonja J. Gill et al. · Clinical Cancer Research · 2023 · 58 citations

Medicine, Oncology, Pharmacology +14

Propagating uncertainties in large-scale hemodynamics models via network uncertainty quantification and reduced-order modeling

Sofia Guzzetti, L.A. Mansilla Alvarez, Pablo J. Blanco et al. · Computer Methods in Applied Mechanics and Engineering · 2019 · 28 citations · Full text

Computing, Computational Engineering, Physics +16

Hierarchical model reduction for incompressible fluids in pipes

Sofia Guzzetti, Simona Perotto, Alessandro Veneziani · International Journal for Numerical Methods in Engineering · 2017 · 22 citations

Computing, Computational Engineering, Mechanical Engineering +14

An integrated modelling approach for targeted degradation: insights on optimization, data requirements and PKPD predictions from semi- or fully-mechanistic models and exact steady state solutions

Sofia Guzzetti, Pablo Morentin Gutierrez · Journal of Pharmacokinetics and Pharmacodynamics · 2023 · 17 citations · Full text

Pharmacy, Pharmacology, Drug Design +16

Platform and algorithm effects on computational fluid dynamics applications in life sciences

Sofia Guzzetti, Tiziano Passerini, Jarosław Sławiński et al. · Future Generation Computer Systems · 2016 · 12 citations

Engineering, Bioengineering, Computational Engineering +16