Concepedia

Abdul M. Deffie

AM

9

Publications

824

Citations

9

H-Index

1988

Active since

Affiliations

The University of Texas MD Anderson Cancer Center(Current)

University of Manitoba

Research Manitoba

Abdul M. Deffie is an author at The University of Texas MD Anderson Cancer Center specializing in cell biology, medicine, and tumor biology.

Top concepts

MedicineCell BiologyTumor BiologyCancer ResearchMolecular BiologyGeneticsPharmacologyCancer BiologyDrug ResistanceNatural Sciences

Publications per year

1988–1998

9

Publications

9

Direct correlation between DNA topoisomerase II activity and cytotoxicity in adriamycin-sensitive and -resistant P388 leukemia cell lines.

Abdul M. Deffie, Janendra K. Batra, Gerald J. Goldenberg · PubMed · 1989 · 263 citations

Hematological Malignancy, Tumor Biology, Drug Resistance Analysis +14

Multifactorial resistance to adriamycin: relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of adriamycin-sensitive and -resistant P388 leukemia.

Abdul M. Deffie, Tawfiq Alam, Charita Seneviratne et al. · PubMed · 1988 · 200 citations

Genome Instability, Agent Melphalan, Dna Damage +14

The tumor suppressor p53 regulates its own transcription.

Abdul M. Deffie, Hongyun Wu, V Reinke et al. · Molecular and Cellular Biology · 1993 · 114 citations · Full text

Genetics, Molecular Biology, Cancer Biology +16

Mutation of Phosphoserine 389 Affects p53 Function in Vivo

Mingming Hao, Andrew M. Lowy, Mini Kapoor et al. · Journal of Biological Chemistry · 1996 · 103 citations · Full text

Evidence for a mutant allele of the gene for DNA topoisomerase II in adriamycin-resistant P388 murine leukemia cells.

Abdul M. Deffie, D J Bosman, Gerald J. Goldenberg · PubMed · 1989 · 46 citations

Mutant Allele, Genetics, Molecular Biology +21

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